Serial In Vitro Marrow Culture in Acute Myelocytic Leukemia
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چکیده
منابع مشابه
Serial in vitro marrow culture in acute myelocytic leukemia.
The in vitro granulocyte colony-forming remission were serially studied during reability of bone marrow from 19 patients mission. Normal in vitro colony formation with acute myelocytic leukemia (AML) was ensued in five of the eight patients studied. studied at the time of initial diagnosis and Three patients did not produce normal serially. Initially 1 8 of the 1 9 patients grew numbers of colo...
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Serial in vitro bone marrow cultures have whereas the mean values for the unstimubeen done on eight patients with acute lated cultdres declined during the same pelymphocytic leukemia. Colony-forming acnod. Relapse in two patients was preceded tivity shows a rapid recovery from low or accompanied by a concomitant decline values into the normal range in all pain colony growth. Colony forming acti...
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Human fibroblast colony formation from bone marrow was performed in liquid culture. Fetal calf serum was used as a stimulator of the fibroblast colony formation. The colony formation took place not only in normal donors, but also in patients with acute leukemia and chronic myelocytic leukemia. At the diagnosis of the disease, significant colony suppression was observed in most cases of acute le...
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Acute myelocytic leukemia (AML) in both children and adults is a more complex and resistant disease than acute lymphocytic leukemia. Progress has been slower and therapy more complicated, but with intensive myelosuppressive induction and further postremission therapy one-third of such patients may now achieve longterm survival and probably be cured.’-5 In the Nordic countries (Denmark, Finland,...
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mic enzyme that converts daunorubicm to a principal metabolite, daunorubicino!, in the presence of NADPH. This enzyme, found in mammalian tissues and studied in rat tissue preparations and normal human blood components, is also present in human leukemic myeloblasts. The enzymes from both normal and leukemic leukocytes require NADPH for activity, have similar kinetics and substrate saturation ch...
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ژورنال
عنوان ژورنال: Blood
سال: 1973
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v42.5.679.679